Institute for Plant Physiology / Justus Liebig University Gießen
PhD position - Phytochrome structure/function
immediately available. The position (E13 65%) is funded for three years by the DFG as part of SFB1078 (Protonation Dynamics in Protein Function) in Berlin – http://www.sfb1078.de.
The aim of the project is to derive an understanding of the functional mechanism underlying photoconversion and signal activation in the phytochrome family of photoreceptors. To this end we will use both X-ray and neutron crystallography to study structural changes associated with photoconversion in various phytochromes. The work is augmented by long-standing co-operations with vibrational spectroscopy and MAS NMR groups in Berlin and Leipzig and has already lead to numerous prominent publications. The successful candidate will work with Dr. Soshi Nagano to create appropriate derivatives of both prokaryotic as well as plant phytochromes for crystallisation and structural determination at the atomic level. The work will include visits to various international research facilities and extensive personal interactions with other members of the Berlin SFB. We have access to advanced robotic facilities to assist us in screening for appropriate crystallisation conditions.
The candidate should have graduated in biochemistry, molecular biology or a related field. Experience in protein biochemistry and/or physicochemical analysis of protein structure/function or would be an advantage. Proficiency in written and spoken English and ability to work constructively in a multinational, interdisciplinary team is important. Applications from women and disabled persons are especially welcome.
If you are interested, please apply immediately by e-mail including a tabular CV:
Professor Jon Hughes
For further details, see the Hughes Group at JLU Gießen