Hello everyone! I am Haoran, originally from China. I started my studies at China Pharmaceutical University and majored in pharmaceutial science. Then I studied Medicinal Chemistry in Shanghai Institute of Materia Medica, Chinese Academy of Sciences at Professor Yushe Yang's group. My Master's thesis was about the design and synthesis of Cap-dependent endonuclease inhibitor. My previous learning experience strengthens my interest in pharmaceutical science. In March 2021, I joined Han Sun's group and started my Ph.D. at the FMP. My doctoral work will focus on proton permeation pathway and ion selectivity of Viroporins investigated by atomistic molecular dynamics simulations.
Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP)
Structural Chemistry and Computational Biophysics
Haoran Liu, born 1995 in Anhui, China
2013-2017 Bachelor of Pharmaceutial Science, China Pharmaceutical University, Nanjing
2017-2020 Master of Medicinal Chemistry, Shanghai Institute of Materia Medica, Chinese Academy of Sciences
My research is focused on understanding ion permeation and gating in non-selective cyclic nucleotide-gated (CNG) ion channels using atomistic molecular dynamics (MD) simulations. CNG channels are key elements for sensory transduction as well as cellular development. Understanding the detailed ion permeation mechanism of the CNG channels is thus important for the biophysical characterization of the CNG channels and also further modulate the gating of the CNGs.